Mechanism of Action

Ultra-low angle arteriotomy procedure delivers tissue-on-tissue overlap for secure vascular closure and no patient implant.

Modified Seldinger

Demands vascular implant or significant manual compression for hemostasis

AXERA® Self-Sealing Arteriotomy

Four times longer surface area provides tissue-on-tissue overlap for secure bonding and intra-arterial pressure promotes hemostasis with no foreign body implants

Technical Advantages of Self Sealing Arteriotomy:

Ultra-Low Angle Arteriotomy
  • Tissue-on-tissue overlap
  • Secure bond
  • No patient implant
Stronger Bond
  • 4x longer tissue tract
  • Significantly greater tissue-on-tissue
  • 2x force necessary to dislodge clot
    in benchtop model
  • Self-sealing arteriotomy creates
    tissue-on-tissue overlap even in tension

Porcine aorta under biaxial strain (physiologically accurate) demonstrates tissue gape in Seldinger approach and tissue overlap in self-sealing arteriotomy
Self-Sealing Check Valve
  • Larger surface area of self-sealing
    arteriotomy combined with arterial
    pressure closes hole and compresses
    tissue, fostering rapid bonding and
    arterial hemostasis
Procedural sheath pulls in pressurized common femoral artery cadaver model